Vagheesh M. Narasimhan

1) Tishkin AA, Ryabogina NE, Agapov SA, Agapov DS, Alekseev AN, Boeskorov GG, Derevianko AP, Dyakonov VM, Enshin DN, Fribus AV, Frolov YV, Grushin SP, Khokhlov AA, Kiryushin KY, Kiryushin YF, Kitov EP, Kosintsev P, Kovtun IV, Makarov NP, Morozov VV, Nikolaev EN, Rykun MP, Savenkova TM, Shchelchkova MV, Shirokov V, Skochina SN, Sherstobitova OS, Slepchenko SM, Solodovnikov KN, Solovyova EN, Stepanov AD, Timoshchenko AA, Vdovin AS, Vybornov AV, Balanovska EV, Dryomov S, Hellenthal G, Kidd K, Krause J, Starikovskaya E, Sukernik R, Tatarinova T, Thomas MG, Zhabagin M, Callan K, Cheronet O, Fernandes D, Keating D, Francesca C, Iliev L, Kearns A, Özdoğan KT, Mah M, Micco A, Michel M, Olalde I, Zalzala F, Mallick S, Rohland N, Pinhasi R+, Narasimhan VM+, Reich D+. Ancient DNA sheds light on the prehistory of the Uralic and Yeniseian peoples. Nature (2025)

2) Xu L, Kun E, Pandey D, Wang JY, Brasil MF+, Singh T+, Narasimhan VM+. The genetic architecture and evolutionary consequences of the human pelvic form. Science (2025)

3) Kun E, Javan EM, Smith O, Gulamali F, de la Fuente J, Flynn BI, Vajrala K, Trutner Z, Jayakumar P, Tucker-Drob EM, Sohail M, Singh T+, Narasimhan VM+. The genetic architecture and evolution of the human skeletal form. Science (2023).

- this was the cover article in Science magazine

- opening plenary talk at the American Society of Human Genetics Conference

- Research excellence paper of the year UT Austin (for the best paper published by UT faculty across all disciplines in a single year)

4) E Kun, Narasimhan VM Fast-evolving genomic regions underlie human brain development. Nature (2023)

4) Narasimhan VM*, Patterson N*, Moorjani P, Rohland N, Bernardos R, Mallick S, Lazaridis I, Nakatsuka N, Olalde I, Lipson M, Kim AM, Olivieri LM, Coppa A, Vidale M, Mallory J, Moiseyev V, Kitov E, Monge J, Adamski N, Alex N, Broomandkhoshbacht N, Candilio F, Callan K, Cheronet O, Culleton BJ, Ferry M, Fernandes D, Freilich S, Gamarra B, Gaudio D, Hajdinjak M, Harney É, Harper TK, Keating D, Lawson AM, Mah M, Mandl K, Michel M, Novak M, Oppenheimer J, Rai N, Sirak K, Slon V, Stewardson K, Zalzala F, Zhang Z, Akhatov G, Bagashev AN, Bagnera A, Baitanayev B, Bendezu-Sarmiento J, Bissembaev AA, Bonora GL, Chargynov TT, Chikisheva T, Dashkovskiy PK, Derevianko A, Dobeš M, Douka K, Dubova N, Duisengali MN, Enshin D, Epimakhov A, Fribus AV, Fuller D, Goryachev A, Gromov A, Grushin SP, Hanks B, Judd M, Kazizov E, Khokhlov A, Krygin AP, Kupriyanova E, Kuznetsov P, Luiselli D, Maksudov F, Mamedov AM, Mamirov TB, Meiklejohn C, Merrett DC, Micheli R, Mochalov O, Mustafokulov S, Nayak A, Pettener D, Potts R, Razhev D, Rykun M, Sarno S, Savenkova TM, Sikhymbaeva K, Slepchenko SM, Soltobaev OA, Stepanova N, Svyatko S, Tabaldiev K, Teschler-Nicola M, Tishkin AA, Tkachev VV, Vasilyev S, Velemínský P, Voyakin D, Yermolayeva A, Zahir M, Zubkov VS, Zubova A, Shinde VS, Lalueza-Fox C, Meyer M, Anthony D, Boivin N, Thangaraj K, Kennett DJ, Frachetti M, Pinhasi R, Reich D. The formation of human populations in South and Central Asia. Science (2019).

- this is the largest sample ancient DNA study ever published, and was the most widely read pre-print in biorxiv history at the time it was published

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5) Shinde V*, Narasimhan VM*, Rohland N, Mallick S, Mah M, Lipson M, Nakatsuka N, Adamski N, Broomandkhoshbacht N, Ferry M, Lawson AM, Michel M, Oppenheimer J, Stewardson K, Jadhav N, Kim YJ, Chatterjee M, Munshi A, Panyam A, Waghmare P, Yadav Y, Patel H, Kaushik A, Thangaraj K, Meyer M, Patterson N, Rai N, Reich D. An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers. Cell (2019).

- merging over 140 libraries for a single sample, this study pushed the boundaries of ancient DNA sequencing technology

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6) Hajdinjak M, Fu Q, Hübner A, Petr M, Mafessoni F, Grote S, Skoglund P, Narasimhan VM, Rougier H, Crevecoeur I, Semal P, Soressi M, Talamo S, Hublin JJ, Gušić I, Kućan Ž, Rudan P, Golovanova LV, Doronichev VB, Posth C, Krause J, Korlević P, Nagel S, Nickel B, Slatkin M, Patterson N, Reich D, Prüfer K, Meyer M, Pääbo S, Kelso J. Reconstructing the genetic history of late Neanderthals. Nature (2018)

7) Narasimhan VM, Hunt KA, Mason D, Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C, Bellary S, Bockett NA, Giorda K, Griffiths CJ, Hemingway H, Jia Z, Kelly MA, Khawaja HA, Lek M, McCarthy S, McEachan R, O'Donnell-Luria A, Paigen K, Parisinos CA, Sheridan E, Southgate L, Tee L, Thomas M, Xue Y, Schnall-Levin M, Petkov PM, Tyler-Smith C, Maher ER, Trembath RC, MacArthur DG, Wright J, Durbin R, van Heel DA. Health and population effects of rare gene knockouts in adult humans with related parents. Science (2016)

- this paper was the first time 10X genomics single cell sequencing was used in a scientific paper, and biologically validated the correctness of the technology.

- the biobank setup by the success of this project has now scaled to >30,000 individuals.

8) Xue Y*, Prado-Martinez J*, Sudmant PH*, Narasimhan VM*, Ayub Q, Szpak M, Frandsen P, Chen Y, Yngvadottir B, Cooper DN, de Manuel M, Hernandez-Rodriguez J, Lobon I, Siegismund HR, Pagani L, Quail MA, Hvilsom C, Mudakikwa A, Eichler EE, Cranfield MR, Marques-Bonet T, Tyler-Smith C, Scally A. Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding. Science (2015)