The Search for the Fly Room

March 24, 2017 • by Nicole Elmer
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The photo of the Fly Room that launched the search. (Dolph Briscoe Center for American History)


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Dr. Thomas Hunt Morgan's Fly Room, 1914. (American Society for Cell Biology)

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Muller in 1922. (Arizona State University)

Patterson made sure Muller would have not only more space, but a new refrigeration unit as well. During scorching Texas summers, Muller previously had to set his bottles of flies in pans of water and drape them in wet cheesecloth to keep them cool. Otherwise, the heat would sterilize them. This new lab became the one in which Muller made his landmark research between 1926-32 on the physiological and genetic effects of radiation on the fruit fly Drosophila, and was able to induce high numbers of mutations in a rapid span of time. X-rays had been used in both medicine and experiments in physics since 1895, but Muller’s discoveries in how radiation affected single genes really made their use valuable in genetics research. Muller recognized that genetic manipulation like this could be used in agriculture, industry, and medicine. So, his work in the Fly Room would bring the space quite a bit of notoriety.

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Southwest side of BIO building, possibly 1940s. (Dolph Briscoe Center for American History)

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The Fly Room at UT. T.S. Painter sits in the rear left. C.P. Oliver looks at the camera, W.S. Stone stands in the back, and Muller is on the far right with his jeweler's loupe. (Indiana University, Lily Library)

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Excerpt from J.T. Patterson's 1925 publication. (Dolph Briscoe Center for American History)

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Hermann Muller’s Office listing, UT Directory 1926, Dolph Briscoe Center for American History

Image from 1940 map of third floor of BIO building (Alexander Archives). Click on image to expand.

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The Fly Room today where the UTEX Culture Collection of Algae is housed.

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Left: Original door leading to constant temperature room. The door’s unusual heaviness and thickness indicates it also might have been where Muller’s X ray machine was housed. Right: Old Sturtevant unit ventilator for constant temperature room. This is the original cooling unit Patterson had installed in the room.

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